BACH2 represses effector programmes to stabilize Treg-mediated immune homeostasis - a new target in tumor immunotherapy?
نویسندگان
چکیده
منابع مشابه
BACH2 represses effector programmes to stabilize Treg-mediated immune homeostasis - a new target in tumor immunotherapy?
Through their functional diversification, distinct lineages of CD4+ T cells play key roles in either driving or constraining immune-mediated pathology and anti-tumor immune responses. Transcription factors are critical in the generation of cellular diversity, and negative regulators antagonistic to alternate fates often act in conjunction with positive regulators to stabilize lineage commitment...
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ژورنال
عنوان ژورنال: Journal for ImmunoTherapy of Cancer
سال: 2013
ISSN: 2051-1426
DOI: 10.1186/2051-1426-1-s1-o14